Yintoni i-lidocaine?

I-Lidocaine sisithomalalisi sendawo, ekwabizwa ngokuba yi-sirocaine, ethathe indawo ye-procaine kwiminyaka yakutshanje kwaye isetyenziswa ngokubanzi kwi-anesthesia yokungena kwindawo kutyando lokuthambisa.Ivimbela ukuvuswa kwe-nerve kunye nokuqhubela phambili ngokuthintela iziteshi ze-ion ze-sodium kwiiseli ze-nerve.Ukunyibilika kwayo kwe-lipid kunye nesantya sokubopha iprotheyini iphezulu kunezo zeprocaine, inamandla okungena kwiseli eyomeleleyo, ukuqala ngokukhawuleza, ixesha elide lesenzo, kunye nokuqina kwesenzo esiphindwe kane kune-procaine.

Izicelo zeklinikhi ziquka i-anesthesia yokungena, i-epidural anesthesia, i-anesthesia yendawo (kuquka i-anesthesia ye-mucosal ngexesha le-thoracoscopy okanye utyando lwesisu), kunye ne-nerve conduction block.Ukuze ukwandise ixesha le-anesthesia kunye nokunciphisa imiphumo emibi efana ne-lidocaine poisoning, i-adrenaline inokongezwa kwi-anesthetic.

I-Lidocaine ingasetyenziselwa ukunyanga i-ventricular premature beats, i-ventricular tachycardia, i-digitalis poisoning, i-ventricular arrhythmias ebangelwa utyando lwe-cardiac kunye ne-catheterization emva kwe-acute myocardial infarction, kubandakanywa ukubetha kwe-ventricular premature, i-ventricular tachycardia, kunye ne-ventricular fibrillation, nayo isetyenziselwa izigulane. ngokuxhuzula okuzingisileyo abangasebenziyo kunye nezinye ii-anticonvulsants kunye ne-anesthesia yendawo okanye yomqolo.Kodwa ngokuqhelekileyo ayisebenzi kwi-supraventricular arrhythmias.

Inkqubela phambili yophando kwi-perioperative intravenous infusion of lidocaine infusion

Ukusetyenziswa rhoqo kweziyobisi ze-opioid kunokubangela ukusabela okubi okuphindaphindiweyo, okukhuthaza uphando olunzulu malunga namachiza angenayo i-opioid analgesic.I-Lidocaine lelinye lawona machiza asebenzayo angeyo-opioid analgesic.Ukulawulwa kwe-perioperative ye-lidocaine kunokunciphisa i-dosage ye-intraoperative ye-opioid, ukukhulula intlungu emva kokuhlinzwa, ukukhawulezisa ukubuyiswa kwe-postoperative ye-gastrointestinal function, ukunciphisa ubude besibhedlele kunye nokukhuthaza ukuvuselelwa emva kokuhlinzwa.

Ukusetyenziswa kweklinikhi ye-lidocaine ye-intravenous ngexesha le-perioperative

1.Nciphisa impendulo yoxinzelelo ngexesha lotyando lwe-anesthesia

2.ukunciphisa umthamo we-intraoperative weziyobisi ze-opioid, ukukhulula intlungu emva kokuhlinzwa

3. Ukukhuthaza ukubuyiswa komsebenzi wesisu, ukunciphisa iziganeko ze-postoperative nausea kunye nokuhlanza (PONV) kunye nokukhubazeka kwengqondo emva kokusebenza (POCD), kunye nokunciphisa ukuhlala esibhedlele.

4.Eminye imisebenzi

Ukongeza kwezi ziphumo zingasentla, i-lidocaine nayo ineziphumo zokunciphisa iintlungu zenaliti yepropofol, inqanda ukusabela kokukhohlela emva kokukhutshwa, kunye nokunciphisa umonakalo we-myocardial.